/ NFL / By Tommy D. SAN FRANCISCO 49ERS VS NEW ORLEANS SAINTS | BOTH TEAMS HAVE HAD A ROUGH TIME, WHICH IS YOUR PICK ? NFL Sunday Night Football 4:25 PM ET OPEN:O/U: 53NO -6.5. LIVE:O/U: 49NO -10 49ers are 7-1 ATS in their last 8 games on FieldTurf. 49ers are 6-2 ATS in their last 8 games as a road underdog. 49ers are 6-2 ATS in their last 8 road games. 49ers are 5-2 ATS in their last 7 games following a double-digit loss at home. 49ers are 7-3 ATS in their last 10 games as an underdog. Saints are 5-1 ATS vs. a team with a losing record. Saints are 3-7 ATS in their last 10 games on FieldTurf. Saints are 2-5 ATS in their last 7 games overall. Saints are 2-6 ATS in their last 8 games following an ATS win. Saints are 1-4 ATS in their last 5 games as a home favorite. Saints are 1-4 ATS in their last 5 home games.