Buffalo Bills vs. Indianapolis Colts | NFL Football Picks, Predictions and Odds

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Tommy D. our NFL expert takes a look at how both teams review their trends and behavior to give us a winning prediction.

PEN:O/U: 52BUF -6.5 LIVE:O/U: 51BUF -6

Bills are 8-0 ATS in their last 8 games overall.

Covers Hot TrendBills are 5-0 ATS in their last 5 games after accumulating more than 250 yards passing in their previous game.
Covers Hot TrendBills are 4-0 ATS in their last 4 games after allowing less than 90 yards rushing in their previous game.
Covers Hot TrendBills are 4-0 ATS in their last 4 games after allowing more than 350 total yards in their previous game.
Covers Hot TrendBills are 7-0 ATS in their last 7 games following a ATS win.
Covers Hot TrendBills are 7-0 ATS in their last 7 games after scoring more than 30 points in their previous game.

Colts are 4-1 ATS in their last 5 road games.

Colts are 15-7 ATS vs. a team with a winning record.

Colts are 4-10 ATS in their last 14 vs. AFC.

Colts are 2-5 ATS in their last 7 playoff road games.

Colts are 1-3-1 ATS in their last 5 games as a road underdog.