07/21/25 Royals vs Cubs: MLB Expert betting analysis and predictions

Royals vs Cubs expert prediction, picks & odds  

The Kansas City Royals (48-52, 39-60-1 O/U) square off against the Chicago Cubs (59-39, 49-43-7 O/U) in what promises to be an intriguing Monday night interleague matchup. This three-game series opener features contrasting narratives: a struggling Royals squad attempting to salvage their season against a Cubs team firmly in playoff contention.

Fresh off a confidence-boosting 7-4 victory over Miami, Kansas City looks to build momentum behind young southpaw Noah Cameron (3-4, 2.31 ERA). Meanwhile, Chicago rebounds from a disappointing 6-1 home defeat to Boston, with veteran right-hander Chris Flexen (5-1, 1.47 ERA) taking the mound to restore order.

Kansas City’s Uphill Battle: Offense Struggles Continue

The Royals find themselves in a precarious position, sitting third in the AL Central with their sub-.500 record reflecting deeper organizational challenges. Their offensive woes have been particularly glaring, ranking 26th league-wide with a disappointing .244/.299/.376 slash line while averaging just 3.43 runs per contest.

Despite these struggles, Kansas City showed signs of life in Sunday’s series finale against Miami. Salvador Perez‘s 15th home run of the season provided crucial power, while Kris Bubic delivered five shutout innings to secure his eighth victory. This performance suggests the Royals possess the talent to compete when everything clicks.

Bobby Witt Jr. remains the franchise cornerstone, posting an impressive .836 OPS with 26 stolen bases, establishing himself among baseball’s premier young talents. His dynamic play provides Kansas City with a legitimate threat in any matchup, regardless of overall team struggles.

Noah Cameron enters this start with renewed confidence after his stellar previous outing, where he pitched 6.2 shutout innings against quality opposition. The young left-hander allowed seven hits while walking two and striking out eight, demonstrating the poise and stuff that made him a highly regarded prospect.

Current Injury Concerns Hampering Kansas City

The Royals’ injury list reads like a medical encyclopedia, significantly impacting their depth and competitiveness:

  • Michael Lorenzen (oblique strain)
  • Mark Canha (elbow inflammation)
  • Daniel Lynch IV (elbow surgery)
  • Cole Ragans (rotator cuff strain)
  • Michael Massey (back injury)
  • Alec Marsh (shoulder impingement)
  • James McArthur (elbow surgery)
  • Hunter Harvey (shoulder strain)

Chicago’s Championship Aspirations: Riding High in NL Central

The Cubs enter this series as the National League Central leaders with an impressive 59-40 record, positioning themselves as legitimate October contenders. Their offensive explosion has been remarkable, ranking fourth league-wide with a .772 team OPS while averaging 5.28 runs per game – a stark contrast to Kansas City’s production.

Chicago’s recent 6-1 setback to Boston served as a reality check, particularly their 2-for-9 performance with runners in scoring position. However, Cade Horton’s 5.2 shutout innings demonstrated the pitching depth that makes this Cubs roster dangerous.

Michael Busch has emerged as a revelation in Chicago’s lineup, blasting 20 home runs while posting a .923 OPS. His seamless integration into the Cubs’ middle order has provided the consistent power threat they’ve long sought.

Chris Flexen brings impressive credentials to Monday’s start, sporting a 1.47 ERA across six decisions with a 5-1 record. However, his last outing against New York raised concerns, allowing three runs on three hits with three walks in just four innings – uncharacteristic control issues for the veteran right-hander.

Chicago’s Injury Report Less Concerning

The Cubs’ injury situation appears more manageable compared to Kansas City:

  • Porter Hodge (shoulder strain)
  • Jameson Taillon (calf injury)
  • Miguel Amaya (oblique strain)
  • Eli Morgan (elbow inflammation)
  • Javier Assad (oblique strain)
  • Justin Steele (elbow surgery)

Betting Analysis: Value and Trends

Recent computer modeling suggests the Royals hold a 55% win probability compared to Chicago’s 45%, indicating potential value on the underdog Kansas City despite their struggles. This statistical edge contradicts conventional wisdom favoring the Cubs’ superior record and home-field advantage.

The Cubs sit 6 games out of a wild card position entering play today and are 4-6 in their last 10 games, while the Royals have been dominant at home with a 36-21 record at Kauffman Stadium. This home-field advantage could prove decisive in a closely contested matchup.

Key betting considerations include:

  • Kansas City’s improved offensive showing in their Miami series
  • Cameron’s recent dominant performance suggesting positive regression
  • Chicago’s struggles with runners in scoring position
  • Flexen’s concerning command issues in his previous start

Pitching Matchup Breakdown

The Cameron vs. Flexen duel presents fascinating stylistic contrasts. Cameron’s left-handed arsenal and improved command make him particularly effective against Chicago’s right-handed heavy lineup. His 2.31 ERA reflects genuine improvement rather than statistical luck, supported by advanced metrics showing decreased walk rates and increased strikeout frequency.

Flexen’s veteran savvy and early-season dominance established him as Chicago’s most reliable starter. However, his recent struggles suggest potential regression, particularly concerning his command – historically his greatest strength. The Royals’ patient approach could exploit any continued control issues.

Game Prediction and Best Bets

This matchup presents compelling arguments for both sides, but several factors favor Kansas City as live underdogs. Cameron’s recent form, combined with the Royals’ improved offensive showing and Chicago’s recent struggles, creates value betting opportunities.

Recommended Plays:

  • Kansas City Royals moneyline (+115) – Primary recommendation
  • Under 8.5 runs – Both pitchers capable of quality outings
  • Bobby Witt Jr. over 1.5 total bases – Star player in favorable matchup

The combination of Kansas City’s home-field advantage, Cameron’s excellent recent form, and Chicago’s offensive inconsistencies creates a scenario where the underdog Royals offer exceptional value at current odds.

Expert Insights

Which team has the better recent momentum heading into this series?

Kansas City appears to have superior momentum despite their overall record. Their 7-4 victory over Miami featured contributions throughout the lineup, while Chicago’s 6-1 loss to Boston highlighted their struggles with clutch hitting. The Royals’ confidence boost from ending a road series on a high note could prove valuable.

How significant is the pitching matchup advantage?

Cameron’s left-handed arsenal presents specific challenges for Chicago’s right-handed heavy lineup, while his recent 6.2 shutout innings demonstrate current form superiority over Flexen’s concerning last outing. The young lefty’s improved command makes him a live underdog in this spot.

What betting trends favor each team?

Kansas City’s 36-21 home record at Kauffman Stadium represents one of baseball’s most significant home-field advantages, while Chicago’s 4-6 record in their last 10 games suggests current struggles. The Cubs’ 2-for-9 performance with runners in scoring position in their last game highlights offensive concerns.

Which injury situations impact this game most?

Kansas City’s extensive injury list, particularly losing Cole Ragans and other key pitchers, significantly impacts their depth. However, Chicago’s loss of Justin Steele to elbow surgery removes their most consistent starter, potentially equalizing the pitching advantage.

Where does the best betting value exist?

The Royals moneyline at +115 offers exceptional value given their 55% computer-modeled win probability. Additionally, the under appears attractive with both pitchers capable of quality outings and Chicago struggling to drive in runs recently.